Evidence for a Symbiosis Island Involved in Horizontal Acquisition of Pederin Biosynthetic Capabilities by the Bacterial Symbiont of Paederus fuscipes Beetles

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منابع مشابه

Evidence for a symbiosis island involved in horizontal acquisition of pederin biosynthetic capabilities by the bacterial symbiont of Paederus fuscipes beetles.

Pederin belongs to a group of antitumor compounds found in terrestrial beetles and marine sponges. It is used by apparently all members of the rove beetle genera Paederus and Paederidus as a chemical defense against predators. However, a recent analysis of the putative pederin biosynthesis (ped) gene cluster strongly suggests that pederin is produced by bacterial symbionts. We have sequenced an...

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this study investigates the cohesive devices used in the textbook of english for the students of psychology. the research questions and hypotheses in the present study are based on what frequency and distribution of grammatical and lexical cohesive devices are. then, to answer the questions all grammatical and lexical cohesive devices in reading comprehension passages from 6 units of 21units th...

فعالیت درماتیتی پدرین و جداسازی باکتری هم‌زیست مرتبط با بیوسنتز آن از سوسک پدروس فوسیپس استان مازندران

Background and purpose: Pederin is a vesicant toxic amide which is found in the haemolymph of the Paederus beetles. It has been considered in studies of cancer treatment with cytotoxicity activity. The present study aimed to review the pederin dermatitis activity from Paederus fuscipes (P. fuscipes) beetles and isolation of symbiotic bacterium associated with pederin biosynthesis. Materials an...

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A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles.

Many drug candidates from marine and terrestrial invertebrates are suspected metabolites of uncultured bacterial symbionts. The antitumor polyketides of the pederin family, isolated from beetles and sponges, are an example. Drug development from such sources is commonly hampered by low yields and the difficulty of sustaining invertebrate cultures. To obtain insight into the true producer and fi...

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ژورنال

عنوان ژورنال: Journal of Bacteriology

سال: 2004

ISSN: 0021-9193,1098-5530

DOI: 10.1128/jb.186.5.1280-1286.2004